Update to Ch4.4 on Mitochondrial Function and Dysfunction [IM4update] #mitochondria

Not all conceptual expansions are immediately translated to clinical therapeutics, but at least we have a broader and more accurate understanding

New video overview provided **above**

Referenced previous work provided below

Mitochondrial signaling and dysfunction: 2022-2023 retrospective

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November 10, 2024
Mitochondrial signaling and dysfunction: 2022-2023 retrospective

I was admittedly impressed by the 2022 publication by Martin Picard and Orian Shirihai in Cell Metabolism 2022 Nov. Today I am taking the time to review my own notes and highlights from that article including the video that was produced in May 2023 to see if I still agree with those conclusions in light of my more recent study of newer publications. As …

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Mitochondrial signaling and dysfunction 2024 update: My complete re-write of the introduction to Chapter 4.4 on "Dysmetabolism & Dysfunctional Organelles"

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November 12, 2024
Mitochondrial signaling and dysfunction 2024 update: My complete re-write of the introduction to Chapter 4.4 on "Dysmetabolism & Dysfunctional Organelles"

Well, after re-reviewing the video and article discussed previously, I was right in my post yesterday, saying that we've reached the 4th level of understanding mitochondrial function and dysfunction. As you can see in the update below, we’ve now traversed four levels of perception of mitochondria:

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