New research shows "consistent pathophysiological alterations after vaccination with COVID-19 vaccines"
Research shows that Cv19 vaccination leads to "pathophysiological alterations" that correlate with abnormal immune responses and increased risk of metabolic disturbances; repeated with each booster?
Key findings and implications:
1) More NFkB = more inflammation
2) Less interferon = less protection = “people’s immune systems, including those of lymphocytes and monocytes, were perhaps in a more vulnerable state”
3) Reduction of CD8+ T cells = less ability to combat viral infections
4) Increase in monocytes = expected to result in more inflammation, more tissue damage, especially as noted in so-called “Covid-19 lung disease”
5) Antibody response was of the IgM and IgG type and was short-lived = these are the wrong types of antibody responses
6) Various metabolic disturbances were noted including [1] increased Hgb-A1c (marker for diabetes and insulin resistance), [2] reductions in potassium and sodium , [3] increased serum creatinine (indicating reduced kidney function)
Source: Cell Discovery [Nature Publishing Group] 2021 Oct. Liu et al. Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccines. 10.1038/s41421-021-00329-3 PDF provided below
Methods: 11 healthy adult volunteers received SARS-CoV-2 vaccine (Vero Cell), inactivated (Beijing Institute of Biological Products Co. Ltd)
Conclusions: “our study recommends additional caution when vaccinating people with pre-existing clinical conditions, including diabetes, electrolyte imbalances, renal dysfunction, and coagulation disorders.”
Corresponding explanations for key findings 1-5 listed above:
NFkB is a nuclear transcription factor that increases expression of pro-inflammatory genes; as such, NFkB is commonly activated by infections and other stressors and is a predictive marker for increased disease risk. NFkB can be regulated by proper diet and nutritional supplementation, as I have extensively detailed since 2005 in published articles and books such as Inflammation Mastery, 4th Edition also published in two separate volumes as Textbook of Clinical Nutrition and Functional Medicine (Volume 1: Chapters 1-4; Volume 2: Chapter 5—Clinical Protocols).
Interferons are generally described as proteins/cytokines that interfere with viral infections; the finding of less interferon following vaccination can be interpreted to indicate paradoxically reduced anti-viral immunity following this vaccination against a viral infection, as noted by the authors who stated, “people’s immune systems, including those of lymphocytes and monocytes, were perhaps in a more vulnerable state.” As noted in my recent video on vitamin D and immune defense against infections, vitamin D supplementation has been shown to increase levels of gamma-interferon.
CD8+ T cells help with antiviral defense by attacking virus-infected cells; obviously therefore, a reduction in CD8+ T cells would paradoxically increase risk for viral infection following this vaccination against viral infection
Increase in monocytes would be expected to promote increased inflammation and tissue damage. The irony is that this vaccine supposedly against Covid19 actually appears to prime inflammatory and immune pathways toward more inflammation and lung damage characteristic of the same Covid19 disease: “Pulmonary macrophages in COVID-19 derived from infiltrating inflammatory monocytes are in a hyperactivated state resulting in a detrimental loop of pro-inflammatory cytokine release and recruitment of cytotoxic effector cells thereby exacerbating tissue damage at the site of infection." Frontiers in Immunology 2021 Jul
IgM and IgG antibody responses are inappropriate for a mucosal viral infection that is not characterized by viremia; the appropriate antibody response for a mucosal infection of the lungs, nose, throat would be an IgA response measured in the mucosa, not an IgM or IgG response measured in the blood. The authors noted that “Overall, IgM showed up earlier than IgG, which was expected. IgG and IgM positivity decreased by day 42 and remained at relatively low levels by day 90 in cohort A. For cohort B, no one developed IgG until after 2nd inoculation. Yet by day 42, IgG positivity reached 100% (Fig. 1c) and sustained until day 56, suggesting that the vaccination protocol for cohort B was more efficacious. By day 90, IgG positivity also reduced to 50%, indicating antibody production did not sustain for a long time.”
Various metabolic disturbances were noted including [1] increased Hgb-A1c (marker for diabetes and insulin resistance), [2] reductions in potassium and sodium, [3] increased serum creatinine (indicating reduced kidney function). These findings are mostly self-explanatory for increased diabetes risk, electrolyte disturbance (which could lead to heart arrhythmia, muscle weakness), and kidney impairment.
Concluding comments:
What the authors wrote: “Historically, vaccine research has been focused on whether or not vaccination could generate neutralizing antibodies to protect against viral infections, whereas short-term and long-term influences of the various newly developed vaccines to human pathophysiology and other perspectives of the human immune system have not been fully investigated.” What the authors meant: We have deviated from scientific norms and safety checks in order to rush these vaccines to market before we have even proven if they work. We don’t have good short-term or long-term data on the risks/safety or pathologic consequences of these vaccines; therefore by definition, their widespread use is reckless and risky.
The authors were very correct to state “our study recommends additional caution when vaccinating people with pre-existing clinical conditions, including diabetes, electrolyte imbalances, renal dysfunction, and coagulation disorders.” Admittedly, their sample size is small and their population was limited to healthy people; these finding would have to be replicated in a larger group (ie, several hundred people) and among people with various health problems (eg, obesity and diabetes) in order to be more representative and generalizable to larger populations.
WHAT IS THE EXPECTATION OF THESE ACCUMULATED EFFECTS IF VACCINATION IS REPEATED EVERY FEW MONTHS? We don’t have the data on this, yet governments are already enforcing mass and repeated vaccination on millions of people.
PDF provided below
Dr Alex Kennerly Vasquez (introduction; brief Bio-CV) writes and teaches for an international audience on various topics ranging from leadership to nutrition to functional inflammology. Major books include Inflammation Mastery, 4th Edition (full-color printing, 1182 pages, equivalent to 25 typical books [averaging 60,000 words each]), which was also published in two separate volumes as Textbook of Clinical Nutrition and Functional Medicine (Volume 1: Chapters 1-4; Volume 2: Chapter 5—Clinical Protocols for Diabetes, Hypertension, Migraine, Fibromyalgia, Rheumatoid Arthritis, Psoriasis, Vasculitis, Dermatomyositis and most other major inflammatory/autoimmune disorders); several sections have been excerpted including Antiviral Strategies and Immune Nutrition (ISBN 1502894890) (aka, Antiviral Nutrition [available as PDF download] and Brain Inflammation in Chronic Pain, Migraine, and Fibromyalgia. Dr Vasquez’s books are available internationally via bookstores such as BookDepository, Amazon.com, Barnes and Noble, ThriftBooks, AbeBooks, BetterWorldBooks, WaterStonesBooks and his new Telegram channel is https://t.me/DrAlexVasquez.