Microbiome and Dysbiosis Video #5: Dysbiosis by Location—The Mouth

What microbes and dysbiotic problems are seen in the mouth? What systemic inflammatory diseases have origins in the mouth? What is “oil pulling” and does it have any scientific basis?

In approximately 2005/2006, I coined the phrase multifocal polydysbiosis to communicate that persons/patients could have dysbiosis in more than one location (multifocal) and could have dysbiosis by more than one microbe at a time. The two classic examples have been rheumatoid arthritis and psoriasis, which are the best defined disorders of autoimmunity induced by dysbiosis (generally) and multifocal polydysbiosis (especially with the more complicated cases). You can see the concept of multifocal polydysbiosis on the cover of the monograph/excerpt (image provided below) from Inflammation Mastery, 4th Edition.

Please note that this video is viewable only on the website at this page (use browser) for Dysbiosis video no5, even though the text is visible in the app

Questions before you begin:

• What microbes and dysbiotic problems are seen in the mouth?

• What systemic inflammatory diseases have origins in the mouth?

• What is “oil pulling” and does it have any scientific basis?

• What mouth-specific treatments improve overall/systemic health?

Video #5 (1 hour and 44 minutes) Dysbiosis by Location—The Mouth

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Listing of Videos Currently Available

The video series outlined below extends from the book “Human Microbiome and Dysbiosis in Clinical Disease” (2015) which is included in the larger textbook Chapter 4 of Inflammation Mastery: Textbook of Clinical Nutrition and Functional Medicine.

1. Video #1 Introduction to Terminology and Concepts: Course Introduction & Clinical Impact of Microbial Molecules: Introduction to the human microbiome and dysbiosis; terms and definitions, clinical relevance and contextualization

2. Video #2 Pathophysiology: Physiologic and Pathologic Mechanisms of Dysbiosis

3. Video #3 Prototypes: Prototypic Clinical Patterns of Dysbiosis-Induced Disease

4. Video #4: Clinical Approach: Testing Microbes vs Treating Dysbiosis and How the Clinical Approach to Dysbiosis Differs from the Approach Used to Treat Infectious Disease

5. Video #5: Dysbiosis by Location—The Mouth

6. Video #6: Dysbiosis by Location—The Sinuses and Respiratory Tract

7. Video #7: Dysbiosis by Location—Genitourinary Tract

8. Video #8: Dysbiosis by Location—Blood, Tissue, Parenchymal Dysbioses

9. Video #9: Dysbiosis by Location—Skin and Environmental Dysbiosis

10. Video Series, Topic #10: Dysbiosis by Location—Gastrointestinal Dysbiosis

    1. Gut Dysbiosis 10.1 on Prototypes: 1 hour, 22 minutes

    2. Gut Dysbiosis 10.2 on Prototypes and Their Solutions: 2 hours

    3. Gut Dysbiosis 10.3 on Solutions: 38 minutes

    4. Gut Dysbiosis 10.4 on Solutions: 33 minutes

    5. Gut Dysbiosis 10.5 on Solutions: Final hour

    6. Gut Dysbiosis 10.6 on Solutions: added in 2020 specific to Gas, Bloating, IBS, and the Gut Microbiome Adaptation to a Healthier Diet (public access)

    7. Gut Dysbiosis 10.7 on Solutions: The Use of Antibiotic Drugs and Endocrine Interventions

Peer-reviewed (independently published) articles related to this material provided by Dr Vasquez:

1. Nutritional and Botanical Treatments Against Silent Infections and Gastrointestinal Dysbiosis Commonly Overlooked Causes of Neuromusculoskeletal Inflammation and Chronic Health Problems. Nutritional Perspectives 2006 academia.edu/39481031

2. Mitochondrial Medicine Arrives to Prime Time in Clinical Care: Nutritional Biochemistry and Mitochondrial Hyperpermeability ("Leaky Mitochondria") Meet Disease Pathogenesis and Clinical Interventions. Integr Med (Encinitas) 2014 Aug;13(4):44-9 pubmed.ncbi.nlm.nih.gov/26770108

3. Reply to "role of Western diet in inflammatory autoimmune diseases" by Manzel et al. In current allergy and asthma reports (volume 14, issue 1, January 2014). Curr Allergy Asthma Rep2014 Aug;14(8):454. doi: 10.1007/s11882-014-0454-4 pubmed.ncbi.nlm.nih.gov/24947682

4. Neuroinflammation in fibromyalgia and CRPS is multifactorial. Nat Rev Rheumatol 2016 Apr;12(4):242. doi: 10.1038/nrrheum.2016.25 pubmed.ncbi.nlm.nih.gov/26935282

5. Biological plausibility of the gut-brain axis in autism. Ann N Y Acad Sci 2017 Nov;1408(1):5-6. doi: 10.1111/nyas.13516 pubmed.ncbi.nlm.nih.gov/29090837

6. Correspondence regarding Cutshall, Bergstrom, Kalish's "Evaluation of a functional medicine approach to treating fatigue, stress, and digestive issues in women" in Complement Ther Clin Pract 2016 May. Complement Ther Clin Pract 2018 May;31:332-333. doi: 10.1016/j.ctcp.2016.10.001 pubmed.ncbi.nlm.nih.gov/27814977

Dr Alex Kennerly Vasquez (introduction; brief Bio-CV) writes and teaches for an international audience on various topics ranging from leadership to nutrition to functional inflammology. Major books include Inflammation Mastery, 4th Edition (full-color printing, 1182 pages, equivalent to 25 typical books [averaging 60,000 words each]), which was also published in two separate volumes as Textbook of Clinical Nutrition and Functional Medicine (Volume 1: Chapters 1-4; Volume 2: Chapter 5—Clinical Protocols for Diabetes, Hypertension, Migraine, Fibromyalgia, Rheumatoid Arthritis, Psoriasis, Vasculitis, Dermatomyositis and most other major inflammatory/autoimmune disorders); several sections have been excerpted including Antiviral Strategies and Immune Nutrition (ISBN 1502894890) (aka, Antiviral Nutrition [available as PDF download] and Brain Inflammation in Chronic Pain, Migraine, and Fibromyalgia. Dr Vasquez’s books are available internationally via bookstores such as BookDepository, Amazon.com, Barnes and Noble, ThriftBooks, AbeBooks, BetterWorldBooks, WaterStonesBooks and his new Telegram channel is https://t.me/DrAlexVasquez.