Microbiome and Dysbiosis Video #6: Dysbiosis by Location—The Sinuses and Respiratory Tract (two videos)
People can have dysbiotic microbial colonizations in multiple locations (multifocal) by different microbes (polydysbiosis); this scenario commonly shows a dose-dependent relationship with disease
People can have dysbiotic microbial colonizations in multiple locations (multifocal) by different microbes (polydysbiosis); this scenario commonly shows a dose-dependent relationship with disease, such as diabesity (eg, gut, mouth, blood) and the prototypic autoimmune conditions rheumatoid arthritis and psoriasis (eg, gut, mouth, genitourinary tract, and—specific to psoriasis and eczema—the skin). The two conditions most noted to have sinorespiratory dysbiosis are systemic lupus erythematosus (ie, SLE, lupus) and granulomatosis with polyangiitis, formerly called Wegener's granulomatosis.
Of additional note is that many people harbor Staphylococcus aureus in their nostrils, and this can serve as a reservoir for infecting surgical wounds; for this reason, disinfecting the nostrils with 5% povidone iodine helps to reduce the risk of surgical infections, as noted for orthopedic surgery and cardiac surgery.
VIDEO: Microbiome and Dysbiosis #6 (1 hour and 34 minutes) Dysbiosis by Location—The Sinuses and Respiratory Tract
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